|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2006-12-6
|
|
pubmed:abstractText |
Activation-induced cell death (AICD) is a major mechanism in the regulation of peripheral tolerance, and caspase-3 represents its major executioner. AICD impairment contributes to the persistence of autoreactive T cells, and defective AICD has been reported in autoimmune thyroiditis as well as in type 1 diabetes mellitus.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0021-972X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
91
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
5064-8
|
|
pubmed:meshHeading |
pubmed-meshheading:16968794-Adolescent,
pubmed-meshheading:16968794-Adult,
pubmed-meshheading:16968794-Age Distribution,
pubmed-meshheading:16968794-Case-Control Studies,
pubmed-meshheading:16968794-Caspase 3,
pubmed-meshheading:16968794-Child,
pubmed-meshheading:16968794-Chronic Disease,
pubmed-meshheading:16968794-Female,
pubmed-meshheading:16968794-Gene Expression,
pubmed-meshheading:16968794-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:16968794-Hormone Replacement Therapy,
pubmed-meshheading:16968794-Humans,
pubmed-meshheading:16968794-Lymphocyte Activation,
pubmed-meshheading:16968794-Male,
pubmed-meshheading:16968794-Middle Aged,
pubmed-meshheading:16968794-Polyendocrinopathies, Autoimmune,
pubmed-meshheading:16968794-T-Lymphocytes,
pubmed-meshheading:16968794-Thyroiditis, Autoimmune
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Impaired caspase-3 expression by peripheral T cells in chronic autoimmune thyroiditis and in autoimmune polyendocrine syndrome-2.
|
|
pubmed:affiliation |
Diabetes Unit, Department of Internal Medicine, University of Siena, Siena, Italy.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
