Source:http://linkedlifedata.com/resource/pubmed/id/16931214
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-8-25
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pubmed:abstractText |
The role of apoptosis in lupus nephritis (LN) is still controversial. One of the key events in the process of apoptosis is activation of caspase-3. Studies of experimental models suggested that activated caspase-3 is a reliable indicator of apoptotic rate, with a favorable comparison against terminal transferase-mediated DNA nick-end labeling (TUNEL) assay. Our aim is to study apoptosis in various forms of LN and its relationship to histomorphological changes and selected laboratory findings by using activated caspase-3 as a novel marker of apoptosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1523-6838
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
410-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16931214-Adolescent,
pubmed-meshheading:16931214-Adult,
pubmed-meshheading:16931214-Aged,
pubmed-meshheading:16931214-Apoptosis,
pubmed-meshheading:16931214-Biological Markers,
pubmed-meshheading:16931214-Caspase 3,
pubmed-meshheading:16931214-Caspases,
pubmed-meshheading:16931214-Child,
pubmed-meshheading:16931214-Enzyme Activation,
pubmed-meshheading:16931214-Female,
pubmed-meshheading:16931214-Gene Expression Profiling,
pubmed-meshheading:16931214-Humans,
pubmed-meshheading:16931214-Immunohistochemistry,
pubmed-meshheading:16931214-Inflammation,
pubmed-meshheading:16931214-Lupus Nephritis,
pubmed-meshheading:16931214-Male,
pubmed-meshheading:16931214-Middle Aged
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pubmed:year |
2006
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pubmed:articleTitle |
Immunohistochemical expression of activated caspase-3 as a marker of apoptosis in glomeruli of human lupus nephritis.
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pubmed:affiliation |
Institute of Pathology, Faculty of Medicine, University of Ljubljana, Slovenia. jera.jeruc@mf.uni-lj.si
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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