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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2006-8-22
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pubmed:abstractText |
Our previous studies have shown that pulsed ultrasound can physically remove soft tissue through cavitation. A new strategy to enhance the cavitation-induced erosion is proposed wherein tissue erosion is initiated by a short, high-intensity sequence of pulses and sustained by lower intensity pulses. We investigated effects of the initiating sequence on erosion and cavitation sustained by lower intensity pulses. Multiple three-cycle pulses at a pulse repetition frequency of 20 kHz delivered by a 788-kHz focused transducer were used for tissue erosion. Fixing the initiating sequence at I(SPPA) of 9000 W/cm2, 16 combinations of different numbers of pulses within the initiating sequence and different sustaining pulse intensities were tested. Results showed: the initiating sequence increases the probability of erosion occurrence and the erosion rate with only slight overall increases in propagated energy; the initiating sequence containing more pulses does not increase the sustained cavitation period; and if extinguished and reinitiated, the sustained cavitation period becomes shorter after each initiation, although the waiting time between adjacent cavitation periods is random. The high-intensity, initiating sequence enhances cavitational tissue erosion and enables erosion at intensities significantly lower than what is required to initiate erosion.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-10461729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-10498515,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-10576273,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-10722920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-10773377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-11053753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-11527597,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-11572377,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-11785829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-12113792,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-12243163,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-12754072,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-12754073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-12837504,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-14962610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-15704435,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-16344129,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-2269722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-3407017,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-4067082,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-595215,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-892812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9004433,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9140187,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9232771,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9483780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9637051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16921893-9809638
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0885-3010
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
53
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1412-24
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pubmed:dateRevised |
2011-9-26
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pubmed:meshHeading |
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pubmed:year |
2006
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pubmed:articleTitle |
A new strategy to enhance cavitational tissue erosion using a high-intensity, Initiating sequence.
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pubmed:affiliation |
Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. zhenx@umich.edu
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pubmed:publicationType |
Journal Article,
In Vitro,
Evaluation Studies,
Research Support, N.I.H., Extramural
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