Linked Life Data

16917482

Source:http://linkedlifedata.com/resource/pubmed/id/16917482

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-8-18
pubmed:abstractText
X-linked juvenile retinoschisis is a rare early-onset retinal degeneration characterized by the formation of cysts and loss of the electroretinogram "b" wave. The affected gene normally codes for retinoschisin (Rs1), a secreted protein containing a large discoidin homology domain. Rs1 seems to be principally synthesized in the photoreceptors, but its structure and spectrum of effects when mutated indicates association with other proteins. The present study searched for retinal proteins capable of interacting with Rs1.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1090-0535
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
892-901
pubmed:dateRevised
2009-5-12
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Retinoschisin forms a multi-molecular complex with extracellular matrix and cytoplasmic proteins: interactions with beta2 laminin and alphaB-crystallin.
pubmed:affiliation
Laboratoire de Physiopathologie Cellulaire et Moléculaire de la Rétine, INSERM U 592, Hópital St. Antoine, Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't