Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-3-14
pubmed:databankReference
pubmed:abstractText
A Drosophila gene encoding a homologue of vertebrate arrestin was isolated by subtractive hybridization and identified as a member of a set of genes that are preferentially expressed in the visual system. This gene encodes a 364-amino acid protein that displays greater than 40% amino acid sequence identity with human and bovine arrestin. Interestingly, the Drosophila homologue lacks the C-terminal sequences that were postulated to interact with rhodopsin during the quenching of the phototransduction cascade in the vertebrate visual response. These findings are discussed in terms of invertebrate phototransduction. The Drosophila gene was mapped cytogenetically to chromosomal position 36D1-2, near the ninaD locus. However, the arrestin gene does not appear to be the ninaD locus, as sequence analysis of three ethylmethane sulfate-induced ninaD mutant alleles reveals no alteration in amino acid sequence.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-16453446, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2105491, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2423011, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2437266, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2449973, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2457447, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2493138, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2580638, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2664782, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-271968, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2827157, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2844605, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2950857, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2985266, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2993262, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2996005, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-2999980, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3006038, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3021528, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3040978, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3080338, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3103129, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3103658, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3116547, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3164688, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-319078, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-334977, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3478675, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-3933112, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-6107856, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-6157589, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-6436059, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-6812046, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-7236108, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-7355973, http://linkedlifedata.com/resource/pubmed/commentcorrection/1689056-994186
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1003-7
pubmed:dateRevised
2010-9-9
pubmed:meshHeading
pubmed-meshheading:1689056-Alleles, pubmed-meshheading:1689056-Amino Acid Sequence, pubmed-meshheading:1689056-Animals, pubmed-meshheading:1689056-Antigens, pubmed-meshheading:1689056-Arrestin, pubmed-meshheading:1689056-Base Sequence, pubmed-meshheading:1689056-DNA, pubmed-meshheading:1689056-Drosophila, pubmed-meshheading:1689056-Eye Proteins, pubmed-meshheading:1689056-Genes, pubmed-meshheading:1689056-Head, pubmed-meshheading:1689056-Membrane Proteins, pubmed-meshheading:1689056-Molecular Sequence Data, pubmed-meshheading:1689056-Nucleic Acid Hybridization, pubmed-meshheading:1689056-Phosphodiesterase Inhibitors, pubmed-meshheading:1689056-RNA, pubmed-meshheading:1689056-Restriction Mapping, pubmed-meshheading:1689056-Salivary Glands, pubmed-meshheading:1689056-Sequence Homology, Nucleic Acid
pubmed:year
1990
pubmed:articleTitle
Isolation and structure of an arrestin gene from Drosophila.
pubmed:affiliation
Howard Hughes Medical Institute, University of California at San Diego, La Jolla 92093.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't