pubmed:abstractText |
No reliable, cost-effective serum test is available for assessment of liver fibrogenesis, the most serious complication of chronic inflammatory liver diseases (CLD). In sera of patients with CLD, we determined the concentration of connective tissue growth factor (CTGF), a secreted downstream mediator of the potent fibrogenic cytokine transforming growth factor beta (TGF-beta).
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pubmed:affiliation |
Institute of Clinical Chemistry and Pathobiochemistry, Central Laboratory, Institute of Medical Statistics, RWTH University Hospital, Aachen, Germany. gressner@twth-aachen.de
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