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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2006-7-3
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pubmed:abstractText |
Potassium is an essential mineral element for plant growth and development. Although it is known that plants absorb and transport K+ through membrane transporters, it remains unclear how these transporters are regulated. Here we show that the protein kinase CIPK23, encoded by the LKS1 gene, regulates K+ uptake under low-K+ conditions. Lesion of LKS1 significantly reduced K+ uptake and caused leaf chlorosis and growth inhibition, whereas overexpression of LKS1 significantly enhanced K+ uptake and tolerance to low K+. We demonstrate that CIPK23 directly phosphorylates the K+ transporter AKT1 and further find that CIPK23 is activated by the binding of two calcineurin B-like proteins, CBL1 and CBL9. We propose a model in which the CBL1/9-CIPK23 pathway ensures activation of AKT1 and enhanced K+ uptake under low-K+ conditions.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/AKT1 protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Arabidopsis Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/CBL protein, Arabidopsis,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Plant,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Protein-Serine-Threonine Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0092-8674
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
125
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1347-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16814720-Animals,
pubmed-meshheading:16814720-Arabidopsis,
pubmed-meshheading:16814720-Arabidopsis Proteins,
pubmed-meshheading:16814720-Base Sequence,
pubmed-meshheading:16814720-Biological Transport, Active,
pubmed-meshheading:16814720-Calcium-Binding Proteins,
pubmed-meshheading:16814720-DNA, Plant,
pubmed-meshheading:16814720-Female,
pubmed-meshheading:16814720-Genes, Plant,
pubmed-meshheading:16814720-Ion Transport,
pubmed-meshheading:16814720-Models, Biological,
pubmed-meshheading:16814720-Mutagenesis,
pubmed-meshheading:16814720-Mutation,
pubmed-meshheading:16814720-Oocytes,
pubmed-meshheading:16814720-Phenotype,
pubmed-meshheading:16814720-Plants, Genetically Modified,
pubmed-meshheading:16814720-Potassium,
pubmed-meshheading:16814720-Potassium Channels,
pubmed-meshheading:16814720-Protein-Serine-Threonine Kinases,
pubmed-meshheading:16814720-Recombinant Proteins,
pubmed-meshheading:16814720-Xenopus laevis
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pubmed:year |
2006
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pubmed:articleTitle |
A protein kinase, interacting with two calcineurin B-like proteins, regulates K+ transporter AKT1 in Arabidopsis.
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pubmed:affiliation |
State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, National Plant Gene Research Centre (Beijing), Beijing 100094, China.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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