Source:http://linkedlifedata.com/resource/pubmed/id/16810557
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2006-6-30
|
| pubmed:abstractText |
While previous reports clearly demonstrated antiproliferative effects of IL-4 on renal cell carcinoma (RCC) in vitro, the administration of IL-4 to patients with metastatic RCC in clinical trials could not recapitulate the promising preclinical results. In the present study we wanted to examine the context of IL-4 action and to establish conditions of enhanced IL-4 efficacy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0340-7004
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
55
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1228-37
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:16810557-Apoptosis,
pubmed-meshheading:16810557-Carcinoma, Renal Cell,
pubmed-meshheading:16810557-Cell Line, Tumor,
pubmed-meshheading:16810557-Cell Proliferation,
pubmed-meshheading:16810557-Cytokines,
pubmed-meshheading:16810557-Flow Cytometry,
pubmed-meshheading:16810557-Humans,
pubmed-meshheading:16810557-Interleukin-4,
pubmed-meshheading:16810557-Kidney Neoplasms,
pubmed-meshheading:16810557-Tumor Necrosis Factor-alpha
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
IL-4 inhibits the TNF-alpha induced proliferation of renal cell carcinoma (RCC) and cooperates with TNF-alpha to induce apoptotic and cytokine responses by RCC: implications for antitumor immune responses.
|
| pubmed:affiliation |
Department of Urology kompetenzzentrum medizin tirol (kmt), Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|