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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
16
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pubmed:dateCreated |
2006-7-3
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pubmed:abstractText |
CTRP1, a member of the CTRP superfamily, consists of an N-terminal signal peptide sequence followed by a variable region, a collagen repeat domain, and a C-terminal globular domain. CTRP1 is expressed at high levels in adipose tissues of LPS-stimulated Sprague-Dawley rats. The LPS-induced increase in CTRP1 gene expression was found to be mediated by TNF-alpha and IL-1beta. Also, a high level of expression of CTRP1 mRNA was observed in adipose tissues of Zucker diabetic fatty (fa/fa) rats, compared to Sprague-Dawley rats in the absence of LPS stimulation. These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-5793
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pubmed:author |
pubmed-author:ChoDae HoDH,
pubmed-author:HanSeung HyunSH,
pubmed-author:KimDo-HyungDH,
pubmed-author:KimHwa YoungHY,
pubmed-author:KimJae HyeongJH,
pubmed-author:KimKeun IlKI,
pubmed-author:KimKun-yongKY,
pubmed-author:LeeChul-HoCH,
pubmed-author:LeeMyeong-SokMS,
pubmed-author:LeeYoung HoYH,
pubmed-author:LimJong-SeokJS,
pubmed-author:YangYoungY,
pubmed-author:YoonDo-YoungDY,
pubmed-author:YoonSukjoonS
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
580
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3953-60
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pubmed:dateRevised |
2007-6-20
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pubmed:meshHeading |
pubmed-meshheading:16806199-Adipose Tissue,
pubmed-meshheading:16806199-Amino Acid Sequence,
pubmed-meshheading:16806199-Animals,
pubmed-meshheading:16806199-Cell Differentiation,
pubmed-meshheading:16806199-Cloning, Molecular,
pubmed-meshheading:16806199-DNA, Complementary,
pubmed-meshheading:16806199-Gene Expression Profiling,
pubmed-meshheading:16806199-Gene Expression Regulation,
pubmed-meshheading:16806199-Humans,
pubmed-meshheading:16806199-Interleukin-1,
pubmed-meshheading:16806199-Lipopolysaccharides,
pubmed-meshheading:16806199-Male,
pubmed-meshheading:16806199-Mice,
pubmed-meshheading:16806199-Molecular Sequence Data,
pubmed-meshheading:16806199-Obesity,
pubmed-meshheading:16806199-Proteins,
pubmed-meshheading:16806199-RNA, Messenger,
pubmed-meshheading:16806199-Rats,
pubmed-meshheading:16806199-Rats, Sprague-Dawley,
pubmed-meshheading:16806199-Rats, Zucker,
pubmed-meshheading:16806199-Sequence Alignment,
pubmed-meshheading:16806199-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue.
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pubmed:affiliation |
Department of Life Science, Research Center for Women's Diseases, Sookmyung Women's University, Seoul 140-742, Republic of Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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