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pubmed-article:16741765pubmed:abstractTextA sample enrichment technique to increase sensitivity in capillary electrophoresis-mass spectrometry (CE-MS) is described. Peptides or glycopeptides are retained and concentrated on a short (3-5-mm) reversed-phase (C18) packed-bed situated in the fused-silica separation capillary and are subsequently released for electrophoretic separation by injection of an organic elutant. The concentration limits of detection are in the high picomolar range with a sheath-flow CE-MS interface.lld:pubmed
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pubmed-article:16741765pubmed:authorpubmed-author:LynenFFlld:pubmed
pubmed-article:16741765pubmed:authorpubmed-author:SandriCClld:pubmed
pubmed-article:16741765pubmed:authorpubmed-author:Van BeeumenJJlld:pubmed
pubmed-article:16741765pubmed:authorpubmed-author:SandraPPlld:pubmed
pubmed-article:16741765pubmed:authorpubmed-author:DevreeseBBlld:pubmed
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pubmed-article:16741765pubmed:volume385lld:pubmed
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pubmed-article:16741765pubmed:year2006lld:pubmed
pubmed-article:16741765pubmed:articleTitleOn-column sample enrichment for the high-sensitivity sheath-flow CE-MS analysis of peptides.lld:pubmed
pubmed-article:16741765pubmed:affiliationLaboratory of Protein Biochemistry and Protein Engineering, Ghent University, K.L. Ledeganckstraat 35, 9000 Gent, Belgium.lld:pubmed
pubmed-article:16741765pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16741765pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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