16741765

Source:http://linkedlifedata.com/resource/pubmed/id/16741765

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0030956, umls-concept:C0370003, umls-concept:C0936012, umls-concept:C2347026
pubmed:issue	4
pubmed:dateCreated	2006-6-2
pubmed:abstractText	A sample enrichment technique to increase sensitivity in capillary electrophoresis-mass spectrometry (CE-MS) is described. Peptides or glycopeptides are retained and concentrated on a short (3-5-mm) reversed-phase (C18) packed-bed situated in the fused-silica separation capillary and are subsequently released for electrophoretic separation by injection of an organic elutant. The concentration limits of detection are in the high picomolar range with a sheath-flow CE-MS interface.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/101134327
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Peptides
pubmed:status	MEDLINE
pubmed:month	Jun
pubmed:issn	1618-2642
pubmed:author	pubmed-author:DevreeseBB, pubmed-author:LynenFF, pubmed-author:SandraPP, pubmed-author:SandriCC, pubmed-author:Van BeeumenJJ
pubmed:issnType	Print
pubmed:volume	385
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	671-7
pubmed:meshHeading	pubmed-meshheading:16741765-Electrophoresis, Capillary, pubmed-meshheading:16741765-Mass Spectrometry, pubmed-meshheading:16741765-Peptides, pubmed-meshheading:16741765-Sensitivity and Specificity
pubmed:year	2006
pubmed:articleTitle	On-column sample enrichment for the high-sensitivity sheath-flow CE-MS analysis of peptides.
pubmed:affiliation	Laboratory of Protein Biochemistry and Protein Engineering, Ghent University, K.L. Ledeganckstraat 35, 9000 Gent, Belgium.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't