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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2006-5-8
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pubmed:abstractText |
Hereditary gingival fibromatosis (HGF) fibroblasts are characterized by an increased production of collagen and transforming growth factor-beta1 (TGF-beta1), resulting in a fibrotic enlargement of the gingiva of affected patients. A common feature of interstitial fibrosis is the occurrence of myofibroblasts, which are regarded as the predominant cells in matrix synthesis. The goal of this article is to describe the presence of myofibroblasts in HGF in order to elucidate the mechanisms underlying HGF gingival overgrowth.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Actins,
http://linkedlifedata.com/resource/pubmed/chemical/CTGF protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Connective Tissue Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Ctgf protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Immediate-Early Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/TGFB1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Tgfb1 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta1,
http://linkedlifedata.com/resource/pubmed/chemical/smooth muscle actin, rat
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0303-6979
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
393-400
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16677327-Actins,
pubmed-meshheading:16677327-Analysis of Variance,
pubmed-meshheading:16677327-Blotting, Western,
pubmed-meshheading:16677327-Connective Tissue Growth Factor,
pubmed-meshheading:16677327-Fibroblasts,
pubmed-meshheading:16677327-Fibromatosis, Gingival,
pubmed-meshheading:16677327-Gingiva,
pubmed-meshheading:16677327-Humans,
pubmed-meshheading:16677327-Immediate-Early Proteins,
pubmed-meshheading:16677327-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:16677327-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16677327-Transforming Growth Factor beta,
pubmed-meshheading:16677327-Transforming Growth Factor beta1
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pubmed:year |
2006
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pubmed:articleTitle |
Heterogeneous presence of myofibroblasts in hereditary gingival fibromatosis.
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pubmed:affiliation |
Department of Oral Diagnosis, University of Campinas Dental School, Piracicaba, São Paulo, Brazil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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