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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-4-17
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pubmed:abstractText |
Vasoactive compounds are known to modulate gene transcription, including nuclear factor kappa B (NF-kappaB), in renal tissues, but the molecular effects of fenoldopam in this setting are not known. The authors used a rat model of surgical acute ischemic nephropathy to test the hypothesis that fenoldopam attenuates ischemia/reperfusion (I/R)-induced NF-kappaB-mediated inflammation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1053-0770
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
179-86
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16616657-Acute Kidney Injury,
pubmed-meshheading:16616657-Animals,
pubmed-meshheading:16616657-DNA,
pubmed-meshheading:16616657-Disease Models, Animal,
pubmed-meshheading:16616657-Fenoldopam,
pubmed-meshheading:16616657-Follow-Up Studies,
pubmed-meshheading:16616657-Gene Expression,
pubmed-meshheading:16616657-Infusions, Intravenous,
pubmed-meshheading:16616657-Insulin-Like Growth Factor I,
pubmed-meshheading:16616657-Ischemia,
pubmed-meshheading:16616657-Kidney,
pubmed-meshheading:16616657-Male,
pubmed-meshheading:16616657-NF-kappa B,
pubmed-meshheading:16616657-Nitric Oxide Synthase Type III,
pubmed-meshheading:16616657-Postoperative Complications,
pubmed-meshheading:16616657-Prospective Studies,
pubmed-meshheading:16616657-Rats,
pubmed-meshheading:16616657-Rats, Sprague-Dawley,
pubmed-meshheading:16616657-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16616657-Signal Transduction,
pubmed-meshheading:16616657-Transcription, Genetic,
pubmed-meshheading:16616657-Vasodilator Agents
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pubmed:year |
2006
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pubmed:articleTitle |
Fenoldopam inhibits nuclear translocation of nuclear factor kappa B in a rat model of surgical ischemic acute renal failure.
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pubmed:affiliation |
Division of Anesthesiology and Critical Care, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA. naravind@mdanderson.org
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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