Source:http://linkedlifedata.com/resource/umls/id/C0060180
MSH: A dopamine D1 receptor agonist that is used as an antihypertensive agent. It lowers blood pressure through arteriolar vasodilation.,CSP: 6-chloro-2,3,4,5-tetrahydro-1-(p-hydroxyphenyl) -3-benzazepine-7,8- diol; dopamine D1 agonist with diuretic and antihypertensive properties, used to treat congestive heart failure, chronic renal failure, and essential hypertension.,NCI: A benzazepine derivative with vasodilatory and antihypertensive properties. Fenoldopam, a dopamine (DA) receptor agonist, binds specifically to peripheral DA1 receptors and to alpha-2 adrenoceptors with moderate affinity. However, this agent exhibits no significant affinity to DA2, other alpha adrenergic, beta adrenergic, muscarinic, or serotonergic receptors. Receptor binding modulates the transmembrane flux of ions, thereby stimulating adenylate cyclase activity, as well as the release of prolactin. This results in vasodilatation, increased renal blood flow thereby enhancing natriuresis and diuresis leading to a lowering in diastolic b