rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-4-17
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pubmed:abstractText |
Vasopressor-induced vasoconstriction may compromise renal and splanchnic blood flow in patients with septic shock, resulting in secondary organ failures. The authors compared the effects of the vasodilatatory agent dopexamine against renal-dose dopamine and placebo in patients with norepinephrine therapy and septic shock, using 24-hour serum creatinine clearance (C(crea)) as a major endpoint. The primary hypothesis to be tested was that dopexamine is more effective than dopamine and that dopamine shows better effects than placebo regarding organ failures and C(crea).
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
pubmed:issn |
1053-0770
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
173-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16616656-Adrenergic alpha-Agonists,
pubmed-meshheading:16616656-Cardiotonic Agents,
pubmed-meshheading:16616656-Creatine,
pubmed-meshheading:16616656-Dopamine,
pubmed-meshheading:16616656-Dopamine Agonists,
pubmed-meshheading:16616656-Double-Blind Method,
pubmed-meshheading:16616656-Female,
pubmed-meshheading:16616656-Follow-Up Studies,
pubmed-meshheading:16616656-Humans,
pubmed-meshheading:16616656-Kidney,
pubmed-meshheading:16616656-Male,
pubmed-meshheading:16616656-Middle Aged,
pubmed-meshheading:16616656-Norepinephrine,
pubmed-meshheading:16616656-Prospective Studies,
pubmed-meshheading:16616656-Shock, Septic,
pubmed-meshheading:16616656-Treatment Outcome,
pubmed-meshheading:16616656-Vasoconstriction
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pubmed:year |
2006
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pubmed:articleTitle |
Comparison of systemic and renal effects of dopexamine and dopamine in norepinephrine-treated septic shock.
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pubmed:affiliation |
Department of Anesthesiology, Ludwig-Maximilians University, Munich, Germany. martin.schmoelz@med.uni-muenchen.de
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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