Source:http://linkedlifedata.com/resource/pubmed/id/16600699
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
2006-4-24
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pubmed:abstractText |
A simple HPLC-UV method was developed for the determination of scutellarin in plasma and different tissues of mice (heart, liver, spleen, lungs and kidneys). The separation was achieved by HPLC on a Hypersil C(18) column with a mobile phase composed of methanol-water-glacial acetic acid (40:60:1). UV detection was used at 335 nm. The calibration curves were linear in all matrices (r(2)>0.997) in the concentration range of 0.1-10 microg/ml for plasma and 0.1-20 microg/g for tissue homogenates, respectively. The method described is suitable for studies on the distribution of scutellarin in different tissues of mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1570-0232
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
835
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
114-8
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pubmed:meshHeading |
pubmed-meshheading:16600699-Animals,
pubmed-meshheading:16600699-Apigenin,
pubmed-meshheading:16600699-Chromatography, High Pressure Liquid,
pubmed-meshheading:16600699-Drug Stability,
pubmed-meshheading:16600699-Glucuronic Acids,
pubmed-meshheading:16600699-Kidney,
pubmed-meshheading:16600699-Liver,
pubmed-meshheading:16600699-Lung,
pubmed-meshheading:16600699-Male,
pubmed-meshheading:16600699-Mice,
pubmed-meshheading:16600699-Myocardium,
pubmed-meshheading:16600699-Reproducibility of Results,
pubmed-meshheading:16600699-Sensitivity and Specificity,
pubmed-meshheading:16600699-Spleen
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pubmed:year |
2006
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pubmed:articleTitle |
Determination of scutellarin in mouse plasma and different tissues by high-performance liquid chromatography.
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pubmed:affiliation |
Pharmaceutical Research Institute, China Pharmaceutical University, Nanjing 210009, PR China.
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pubmed:publicationType |
Journal Article
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