rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
1991-12-18
|
pubmed:abstractText |
Pleomorphic peripheral T-cell lymphomas (PPTL) arising primarily in the skin are uncommon. The observation of pleomorphic T-cell lymphoma composed of 100% CD30+ cells is rare. We report the case of a woman in whom such a tumor manifested itself with a single cutaneous lesion. It was composed of medium to large cells expressing markers of helper/inducer T-lymphocytes, as well as activation (CD30) and proliferation antigens (Ki-67), but not the CD25 activation antigen. The lesion was excised and the patient is alive and disease free 2 years after the diagnosis. This case confirms previous reports about the favorable course of some cutaneous pleomorphic lymphomas, and shows that the activation antigen expression and proliferation antigen (Ki-67) expression do not seem to worsen the prognosis.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0193-1091
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
13
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
503-8
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:1659246-Antigens, CD,
pubmed-meshheading:1659246-Antigens, CD30,
pubmed-meshheading:1659246-Antigens, Neoplasm,
pubmed-meshheading:1659246-Female,
pubmed-meshheading:1659246-Gene Rearrangement, beta-Chain T-Cell Antigen Receptor,
pubmed-meshheading:1659246-Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor,
pubmed-meshheading:1659246-Humans,
pubmed-meshheading:1659246-Ki-67 Antigen,
pubmed-meshheading:1659246-Lymphoma, Non-Hodgkin,
pubmed-meshheading:1659246-Lymphoma, T-Cell, Cutaneous,
pubmed-meshheading:1659246-Middle Aged,
pubmed-meshheading:1659246-Nuclear Proteins,
pubmed-meshheading:1659246-Skin Neoplasms
|
pubmed:year |
1991
|
pubmed:articleTitle |
Primary cutaneous pleomorphic T-cell lymphoma expressing CD30 antigen.
|
pubmed:affiliation |
First Clinic of Dermatology, University of Milan, Italy.
|
pubmed:publicationType |
Journal Article,
Case Reports
|