rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0021966,
umls-concept:C0025519,
umls-concept:C0040132,
umls-concept:C0040300,
umls-concept:C0084785,
umls-concept:C0086418,
umls-concept:C0683941,
umls-concept:C1314939,
umls-concept:C1384616,
umls-concept:C1415537,
umls-concept:C2347318
|
pubmed:issue |
4
|
pubmed:dateCreated |
2006-4-4
|
pubmed:abstractText |
Benign and malignant thyroid tumours are characterized by alterations of the expression level of thyroid-specific genes involved in the iodide metabolism. Imbalance in the levels of transcription factors has been recognized as a critical molecular event in the development of neoplasm. The delineation of eventual correlations existing between the expression of transcription factors and of putative target genes in physiological and pathological conditions could be relevant to better understand tumorigenesis.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/HHEX protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Homeodomain Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Iodides,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/PAX8 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Paired Box Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/thyroid nuclear factor 1
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0300-0664
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
64
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
398-404
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16584511-Case-Control Studies,
pubmed-meshheading:16584511-Cluster Analysis,
pubmed-meshheading:16584511-Gene Expression Profiling,
pubmed-meshheading:16584511-Homeodomain Proteins,
pubmed-meshheading:16584511-Humans,
pubmed-meshheading:16584511-Iodides,
pubmed-meshheading:16584511-Nuclear Proteins,
pubmed-meshheading:16584511-Paired Box Transcription Factors,
pubmed-meshheading:16584511-RNA, Messenger,
pubmed-meshheading:16584511-Statistics, Nonparametric,
pubmed-meshheading:16584511-Thyroid Diseases,
pubmed-meshheading:16584511-Thyroid Gland,
pubmed-meshheading:16584511-Transcription Factors
|
pubmed:year |
2006
|
pubmed:articleTitle |
HEX, PAX-8 and TTF-1 gene expression in human thyroid tissues: a comparative analysis with other genes involved in iodide metabolism.
|
pubmed:affiliation |
Department of Clinical Biology, Institut Gustave-Roussy and Commissariat à l'Energie Atomique LRC 29V, Villejuif, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|