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pubmed-article:16534415pubmed:abstractTextMice lacking the pertussis toxin-sensitive G-protein subunit Gi alpha2 spontaneously develop colitis and colon cancer. In the gut, arachidonate-derived prostaglandin E2 (PGE2) modulates intestinal immune responses and epithelial restitution and is derived largely from subepithelial myofibroblasts.lld:pubmed
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pubmed-article:16534415pubmed:articleTitleDefective arachidonate release and PGE2 production in Gi alpha2-deficient intestinal and colonic subepithelial myofibroblasts.lld:pubmed
pubmed-article:16534415pubmed:affiliationDepartment of Pathology, University of California Irvine, Irvine, California 92697-4800, USA. redwards@uci.edulld:pubmed
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