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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-2-20
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pubmed:abstractText |
The insulin-like growth factor (IGF) system plays important roles in cancer; blocking IGF signaling has been shown to have therapeutic effects on tumor growth. Many studies have focused on the effect of IGF-I, but few have addressed IGF-II. To assess the role of IGF-II in cancer, we analyzed IGF-II expression in ovarian cancer and examined its association with disease characteristics and prognosis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1208-14
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16489075-Adult,
pubmed-meshheading:16489075-Aged,
pubmed-meshheading:16489075-Aged, 80 and over,
pubmed-meshheading:16489075-Disease Progression,
pubmed-meshheading:16489075-Epithelial Cells,
pubmed-meshheading:16489075-Estrogen Receptor alpha,
pubmed-meshheading:16489075-Female,
pubmed-meshheading:16489075-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16489075-Humans,
pubmed-meshheading:16489075-Insulin-Like Growth Factor Binding Protein 3,
pubmed-meshheading:16489075-Insulin-Like Growth Factor II,
pubmed-meshheading:16489075-Middle Aged,
pubmed-meshheading:16489075-Neoplasm Staging,
pubmed-meshheading:16489075-Ovarian Neoplasms,
pubmed-meshheading:16489075-RNA, Neoplasm,
pubmed-meshheading:16489075-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16489075-Survival Analysis,
pubmed-meshheading:16489075-Tumor Markers, Biological
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pubmed:year |
2006
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pubmed:articleTitle |
The relationship of insulin-like growth factor-II, insulin-like growth factor binding protein-3, and estrogen receptor-alpha expression to disease progression in epithelial ovarian cancer.
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pubmed:affiliation |
Department of Epidemiology and Public Health, Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut 06520-8034, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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