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pubmed-article:16476037pubmed:abstractTextTumor necrosis factor (TNF)-alpha is associated with chronic gingival inflammation and reported to induce gingival overgrowth (GO), while phenytoin (PHT) is also known to be a causative agent of GO. We examined the synergistic effect of PHT and TNF-alpha on collagen metabolism in human gingival fibroblasts (HGFs).lld:pubmed
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pubmed-article:16476037pubmed:articleTitleEffect of phenytoin on collagen accumulation by human gingival fibroblasts exposed to TNF-alpha in vitro.lld:pubmed
pubmed-article:16476037pubmed:affiliationDepartment of Oral Frontier Biology, Osaka University Graduate School of Dentistry, Suita-Osaka, Japan.lld:pubmed
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