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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-2-14
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pubmed:abstractText |
Tumor necrosis factor (TNF)-alpha is associated with chronic gingival inflammation and reported to induce gingival overgrowth (GO), while phenytoin (PHT) is also known to be a causative agent of GO. We examined the synergistic effect of PHT and TNF-alpha on collagen metabolism in human gingival fibroblasts (HGFs).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1354-523X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
156-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16476037-Anticonvulsants,
pubmed-meshheading:16476037-Cell Proliferation,
pubmed-meshheading:16476037-Cells, Cultured,
pubmed-meshheading:16476037-Collagen,
pubmed-meshheading:16476037-Drug Synergism,
pubmed-meshheading:16476037-Endocytosis,
pubmed-meshheading:16476037-Fibroblasts,
pubmed-meshheading:16476037-Gingiva,
pubmed-meshheading:16476037-Humans,
pubmed-meshheading:16476037-Integrin alpha2beta1,
pubmed-meshheading:16476037-Integrins,
pubmed-meshheading:16476037-Matrix Metalloproteinase 1,
pubmed-meshheading:16476037-Matrix Metalloproteinase 2,
pubmed-meshheading:16476037-Phenytoin,
pubmed-meshheading:16476037-Protein Subunits,
pubmed-meshheading:16476037-Tissue Inhibitor of Metalloproteinase-1,
pubmed-meshheading:16476037-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
Effect of phenytoin on collagen accumulation by human gingival fibroblasts exposed to TNF-alpha in vitro.
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pubmed:affiliation |
Department of Oral Frontier Biology, Osaka University Graduate School of Dentistry, Suita-Osaka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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