| pubmed-article:16422410 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16422410 | lifeskim:mentions | umls-concept:C0009924 | lld:lifeskim |
| pubmed-article:16422410 | lifeskim:mentions | umls-concept:C0041618 | lld:lifeskim |
| pubmed-article:16422410 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:16422410 | pubmed:dateCreated | 2006-1-20 | lld:pubmed |
| pubmed-article:16422410 | pubmed:abstractText | Ultrasound contrast agents enhance echoes from the microvasculature and enable the visualization of flow in smaller vessels. Here, we optically and acoustically investigate microbubble oscillation and echoes following insonation with a 10 MHz center frequency pulse. A high-speed camera system with a temporal resolution of 10 ns, which provides two-dimensional (2-D) frame images and streak images, is used in optical experiments. Two confocally aligned transducers, transmitting at 10 MHz and receiving at 5 MHz, are used in acoustical experiments in order to detect subharmonic components. Results of a numerical evaluation of the modified Rayleigh-Plesset equation are used to predict the dynamics of a microbubble and are compared to results of in vitro experiments. From the optical observations of a single microbubble, nonlinear oscillation, destruction, and radiation force are observed. The maximum bubble expansion, resulting from insonation with a 20-cycle, 10-MHz linear chirp with a peak negative pressure of 3.5 MPa, has been evaluated. For an initial diameter ranging from 1.5 to 5 microm, a maximum diameter less than 8 microm is produced during insonation. Optical and acoustical experiments provide insight into the mechanisms of destruction, including fragmentation and active diffusion. High-frequency pulse transmission may provide the opportunity to detect contrast echoes resulting from a single pulse, may be robust in the presence of tissue motion, and may provide the opportunity to incorporate high-frequency ultrasound into destruction-replenishment techniques. | lld:pubmed |
| pubmed-article:16422410 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16422410 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16422410 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16422410 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16422410 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:16422410 | pubmed:issn | 0885-3010 | lld:pubmed |
| pubmed-article:16422410 | pubmed:author | pubmed-author:YangSunS | lld:pubmed |
| pubmed-article:16422410 | pubmed:author | pubmed-author:FerraraKather... | lld:pubmed |
| pubmed-article:16422410 | pubmed:author | pubmed-author:DaytonPaul... | lld:pubmed |
| pubmed-article:16422410 | pubmed:author | pubmed-author:KruseDustin... | lld:pubmed |
| pubmed-article:16422410 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16422410 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:16422410 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16422410 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16422410 | pubmed:pagination | 1981-91 | lld:pubmed |
| pubmed-article:16422410 | pubmed:dateRevised | 2010-12-3 | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:meshHeading | pubmed-meshheading:16422410... | lld:pubmed |
| pubmed-article:16422410 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16422410 | pubmed:articleTitle | High-frequency dynamics of ultrasound contrast agents. | lld:pubmed |
| pubmed-article:16422410 | pubmed:affiliation | UC Davis, Davis, CA 95616, USA. ywsun@ucdavis.edu | lld:pubmed |
| pubmed-article:16422410 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16422410 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
