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rdf:type |
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lifeskim:mentions |
umls-concept:C0008059,
umls-concept:C0011854,
umls-concept:C0035647,
umls-concept:C0035820,
umls-concept:C0229671,
umls-concept:C0262950,
umls-concept:C0332307,
umls-concept:C0441889,
umls-concept:C0449438,
umls-concept:C0538161,
umls-concept:C1709059
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pubmed:issue |
6
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pubmed:dateCreated |
2005-12-2
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pubmed:abstractText |
Children and adolescents with type 1 (insulin-dependent) diabetes mellitus (T1DM) show several impairment of bone metabolism and structure, resulting in a higher risk of decreased bone mass and its related complications later in life. Alterations of the nuclear factor-kappaB ligand (RANKL)/osteoprotegerin (OPG) system have been implicated in several metabolic bone diseases characterized by increased osteoclast differentiation and activation and enhanced bone resorption.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
153
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
879-85
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16322394-Adolescent,
pubmed-meshheading:16322394-Bone Density,
pubmed-meshheading:16322394-Bone and Bones,
pubmed-meshheading:16322394-Child,
pubmed-meshheading:16322394-Child, Preschool,
pubmed-meshheading:16322394-Diabetes Mellitus, Type 1,
pubmed-meshheading:16322394-Female,
pubmed-meshheading:16322394-Glycoproteins,
pubmed-meshheading:16322394-Hemoglobin A, Glycosylated,
pubmed-meshheading:16322394-Humans,
pubmed-meshheading:16322394-Male,
pubmed-meshheading:16322394-Osteoprotegerin,
pubmed-meshheading:16322394-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:16322394-Receptors, Tumor Necrosis Factor
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pubmed:year |
2005
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pubmed:articleTitle |
Osteoprotegerin serum levels in children with type 1 diabetes: a potential modulating role in bone status.
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pubmed:affiliation |
Department of Paediatrics, A Meyer Children's Hospital,Via Luca Giordano 13, 50132 Florence, Italy.
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pubmed:publicationType |
Journal Article
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