Source:http://linkedlifedata.com/resource/umls/id/C0538161
MSH: A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that inhibits both CELL DIFFERENTIATION and function of OSTEOCLASTS by inhibiting the interaction between RANK LIGAND and RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B.,CSP: osteoclastogenesis inhibitor; secreted protein that regulates bone density; member of the TNF receptor superfamily,NCI: Widely expressed by estrogen- and glucocorticoid-regulated human TNFRSF11B Gene (TNFR Family), 401-aa 46-kDa (precursor) N-glycosylated homodimeric secreted Tumor Necrosis Factor Receptor Superfamily Member 11B contains a blocked N-terminus, 4 TNFR-Cys repeats, 2 death domains, and sialic acid residues. TNFRSF11B acts as a regulator of bone homeostasis and osteoclast development. A decoy receptor for RANKL (TNFSF11/OPGL), TNFRSF11B inhibits activation of osteoclasts (osteoclastogenesis) and promotes osteoclast apoptosis. TNFRSF11B may also act as decoy receptor for TRAIL, prote