Connective tissue growth factor (CTGF) has been implicated in the pathogenesis of hepatic fibrosis and is elevated in the serum of children with biliary atresia (BA). The objective of this study was to evaluate hepatic CTGF messenger RNA (mRNA) expression and its relationship to hepatic histology in children with BA.
Department of Pediatrics, The Pediatric Liver Center, The Children's Hospital, University of Colorado School of Medicine, Denver, CO 80218, USA. narkewicz.michael@tchden.org