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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-3-27
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pubmed:abstractText |
Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer (LABC). The IBC phenotype is characterized by an infiltrative growth pattern, increased (lymph)angiogenesis and the propensity to invade dermal lymphatics. In pancreatic cancer, interactions between caveolin-1 and RhoC GTPase, a key molecule in causing the IBC phenotype, regulate tumour cell motility and invasion. In this study we sought to investigate the role of caveolin-1 and -2 in IBC cell lines and in human IBC samples.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0167-6806
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-28
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pubmed:meshHeading |
pubmed-meshheading:16244790-Adult,
pubmed-meshheading:16244790-Aged,
pubmed-meshheading:16244790-Aged, 80 and over,
pubmed-meshheading:16244790-Breast Neoplasms,
pubmed-meshheading:16244790-Carcinoma, Ductal, Breast,
pubmed-meshheading:16244790-Carcinoma, Lobular,
pubmed-meshheading:16244790-Caveolin 1,
pubmed-meshheading:16244790-Caveolin 2,
pubmed-meshheading:16244790-Cell Line, Tumor,
pubmed-meshheading:16244790-DNA Methylation,
pubmed-meshheading:16244790-Female,
pubmed-meshheading:16244790-Gene Expression Profiling,
pubmed-meshheading:16244790-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16244790-Humans,
pubmed-meshheading:16244790-Immunoenzyme Techniques,
pubmed-meshheading:16244790-Middle Aged,
pubmed-meshheading:16244790-Neoplasm Staging,
pubmed-meshheading:16244790-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16244790-RNA, Messenger,
pubmed-meshheading:16244790-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16244790-Tumor Markers, Biological,
pubmed-meshheading:16244790-Up-Regulation,
pubmed-meshheading:16244790-rho GTP-Binding Proteins
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pubmed:year |
2006
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pubmed:articleTitle |
Overexpression of caveolin-1 and -2 in cell lines and in human samples of inflammatory breast cancer.
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pubmed:affiliation |
Translational Cancer Research Group Antwerp, Lab Pathology, University of Antwerp/University Hospital Antwerp, Edegem, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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