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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
22
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pubmed:dateCreated |
2005-10-20
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pubmed:abstractText |
[reaction: see text] Nine fluorescently labeled structurally varied polyguanidino dendrimers based on diamino acid monomeric units were individually synthesized in an efficient, scalable sequence using a trifluoroacetamide protecting group-perguanidinylation strategy. While the dendrimers varied significantly in their ability to enter a human lymphocyte cell line, the best transporters out-performed an oligoarginine reference standard.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
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pubmed:issn |
1523-7060
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
7
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
4815-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
|
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pubmed:year |
2005
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pubmed:articleTitle |
Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake.
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|
pubmed:affiliation |
Department of Chemistry and Department of Molecular Pharmacology, Stanford University, California 94305-5080, USA. wenderp@stanford.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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