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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
18
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pubmed:dateCreated |
2005-9-16
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pubmed:abstractText |
Persistent interleukin-8 (IL-8) production contributes to chronic inflammation of the stomach. The proinflammatory IL-1beta polymorphisms, which enhance the cytokine production, are associated with increased risk of gastric cancer. The -251A/T polymorphism of the IL-8 promoter is involved in several human diseases. Particularly, the -251A is associated with decreased risk of colorectal cancer. We aimed to determine whether the -251 allele resulting in high IL-8 expression was associated with increased risk of gastric carcinoma.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1078-0432
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pubmed:author |
pubmed-author:ChangFull-YoungFY,
pubmed-author:ChaoYeeY,
pubmed-author:HsuHou-ChingHC,
pubmed-author:LanKeng-HsinKH,
pubmed-author:LeeShou-DongSD,
pubmed-author:LeeWei-PingWP,
pubmed-author:LiAnna Fen-YauAF,
pubmed-author:LiChung-PinCP,
pubmed-author:LinEn-JuEJ,
pubmed-author:LinYi-PingYP,
pubmed-author:SheuMeei-LingML,
pubmed-author:TaiDar-InDI,
pubmed-author:YenShang-HeuSH
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6431-41
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16166417-Adult,
pubmed-meshheading:16166417-Aged,
pubmed-meshheading:16166417-Alleles,
pubmed-meshheading:16166417-Base Sequence,
pubmed-meshheading:16166417-Case-Control Studies,
pubmed-meshheading:16166417-Cell Line, Tumor,
pubmed-meshheading:16166417-Chi-Square Distribution,
pubmed-meshheading:16166417-China,
pubmed-meshheading:16166417-Female,
pubmed-meshheading:16166417-Gene Frequency,
pubmed-meshheading:16166417-Genotype,
pubmed-meshheading:16166417-Helicobacter Infections,
pubmed-meshheading:16166417-Helicobacter pylori,
pubmed-meshheading:16166417-Humans,
pubmed-meshheading:16166417-Interleukin-8,
pubmed-meshheading:16166417-Male,
pubmed-meshheading:16166417-Middle Aged,
pubmed-meshheading:16166417-Odds Ratio,
pubmed-meshheading:16166417-Polymorphism, Single Nucleotide,
pubmed-meshheading:16166417-Promoter Regions, Genetic,
pubmed-meshheading:16166417-Risk Factors,
pubmed-meshheading:16166417-Stomach Neoplasms,
pubmed-meshheading:16166417-Tumor Cells, Cultured
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pubmed:year |
2005
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pubmed:articleTitle |
The -251T allele of the interleukin-8 promoter is associated with increased risk of gastric carcinoma featuring diffuse-type histopathology in Chinese population.
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pubmed:affiliation |
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, Taiwan. wleemc@yahoo.com
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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