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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-12-15
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pubmed:abstractText |
Expression of the inflammatory chemokine CCL5 (RANTES) by tumor cells is thought to correlate with the progression of several cancers. CCL5 was shown to induce breast cancer cell migration, mediated by the receptor CCR5. A CCR5 antagonist was demonstrated to inhibit experimental breast tumor growth. Recently, CCL5 and CCR5 mRNA expression was reported in prostate cancer (PCa) tissues. Herein, we characterized CCL5 and CCR5 expression in cultures of PCa cells and explored possible functions of CCL5 in PCa progression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amides,
http://linkedlifedata.com/resource/pubmed/chemical/CCL5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL5,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CC,
http://linkedlifedata.com/resource/pubmed/chemical/Quaternary Ammonium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR5,
http://linkedlifedata.com/resource/pubmed/chemical/TAK 779
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
124-34
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16161154-Adenocarcinoma,
pubmed-meshheading:16161154-Amides,
pubmed-meshheading:16161154-Autocrine Communication,
pubmed-meshheading:16161154-Cell Line, Tumor,
pubmed-meshheading:16161154-Cell Membrane,
pubmed-meshheading:16161154-Cell Proliferation,
pubmed-meshheading:16161154-Chemokine CCL5,
pubmed-meshheading:16161154-Chemokines, CC,
pubmed-meshheading:16161154-Disease Progression,
pubmed-meshheading:16161154-Flow Cytometry,
pubmed-meshheading:16161154-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16161154-Humans,
pubmed-meshheading:16161154-Immunohistochemistry,
pubmed-meshheading:16161154-Male,
pubmed-meshheading:16161154-Neoplasm Invasiveness,
pubmed-meshheading:16161154-Prostatic Neoplasms,
pubmed-meshheading:16161154-Quaternary Ammonium Compounds,
pubmed-meshheading:16161154-RNA, Messenger,
pubmed-meshheading:16161154-Receptors, CCR5,
pubmed-meshheading:16161154-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2006
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pubmed:articleTitle |
Expression of CCL5 (RANTES) and CCR5 in prostate cancer.
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pubmed:affiliation |
Department of Research, Northport Veterans Affairs Medical Center, Northport, New York 11768, USA. Gayle.Vaday@med.va.gov
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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