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rdf:type |
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lifeskim:mentions |
umls-concept:C0014653,
umls-concept:C0017262,
umls-concept:C0025663,
umls-concept:C0040300,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0205349,
umls-concept:C0243077,
umls-concept:C0332453,
umls-concept:C0332461,
umls-concept:C0392762,
umls-concept:C0599161,
umls-concept:C0623362,
umls-concept:C0741968,
umls-concept:C0936012,
umls-concept:C1274040,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2006-1-25
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|
pubmed:abstractText |
The balance between degradation and synthesis of extracellular matrix determines its content in atherosclerotic tissue. To examine the role of expression balance of matrix metalloproteinases (MMPs) to their inhibitors, tissue inhibitors of metalloproteinases (TIMPs) and tissue factor pathway inhibitor-2 (TFPI-2) in the development and disruption of atherosclerotic plaque, these gene expressions in human carotid plaque were quantitatively determined by real-time reverse transcription (RT)-polymerase chain reaction (PCR) method.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0021-9150
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pubmed:author |
pubmed-author:HigashiToshioT,
pubmed-author:HigashikataTakeoT,
pubmed-author:IiharaKojiK,
pubmed-author:Ishibashi-UedaHatsueH,
pubmed-author:IwaseTakashiT,
pubmed-author:MiyamotoSusumuS,
pubmed-author:NagataIzumiI,
pubmed-author:NagayaNoritoshiN,
pubmed-author:SakamotoAijiA,
pubmed-author:TomoikeHitonobuH,
pubmed-author:YamagishiMasakazuM
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pubmed:issnType |
Print
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pubmed:volume |
185
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
165-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16039658-Aged,
pubmed-meshheading:16039658-Carotid Arteries,
pubmed-meshheading:16039658-Carotid Artery Diseases,
pubmed-meshheading:16039658-Endarterectomy, Carotid,
pubmed-meshheading:16039658-Gene Expression,
pubmed-meshheading:16039658-Genetic Markers,
pubmed-meshheading:16039658-Humans,
pubmed-meshheading:16039658-Immunohistochemistry,
pubmed-meshheading:16039658-Male,
pubmed-meshheading:16039658-Matrix Metalloproteinases,
pubmed-meshheading:16039658-RNA, Messenger,
pubmed-meshheading:16039658-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16039658-Severity of Illness Index,
pubmed-meshheading:16039658-Tissue Inhibitor of Metalloproteinases
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pubmed:year |
2006
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pubmed:articleTitle |
Altered expression balance of matrix metalloproteinases and their inhibitors in human carotid plaque disruption: results of quantitative tissue analysis using real-time RT-PCR method.
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pubmed:affiliation |
Division of Cardiovascular Medicine and Bioscience, National Cardiovascular Center and Research Institute, 5-7-1 Fujishiro-dai, Suita, Osaka 565-8565, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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