Linked Life Data

16009522

Source:http://linkedlifedata.com/resource/pubmed/id/16009522

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-3
pubmed:dateCreated
2005-9-12
pubmed:abstractText
Long-term and repeated exposure of ultraviolet (UV) light, a harmful environmental stress, on the skin often induces chronic skin diseases, such as skin cancer as well as photo-aging (premature skin aging), and the mechanisms of these skin damages are closely associated with up-regulation of matrix metalloproteinases (MMPs) activities. Here, we investigated the effect of quercetin-3-O-beta-d-(6''-feruloyl)-galactopyranoside isolated from the stems of Viola hondoensis (Violaceae) on the expression of MMPs in UV-irradiated human skin fibroblasts in vitro. Quercetin-3-O-beta-d-(6''-feruloyl)-galactopyranoside markedly reduced UV-induced MMP-1 expression at the protein levels in a dose-dependent manner. Our report is the first description for the ability of quercetin-3-O-beta-d-(6''-feruloyl)-galactopyranoside to regulate UV-induced MMP-1 expression.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0378-8741
pubmed:author
pubmed:issnType
Print
pubmed:day
3
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
176-9
pubmed:dateRevised
2008-7-2
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The effect of flavonol glycoside on the expressions of matrix metalloproteinase-1 in ultraviolet-irradiated cultured human skin fibroblasts.
pubmed:affiliation
Department of Dermatology, Seoul National University College of Medicine and Laboratory of Cutaneous Aging Research, Clinical Research Institute, Seoul National University Hospital, Seoul 110-744, Republic of Korea. himun@snu.ac.kr
pubmed:publicationType
Journal Article, Retracted Publication, Research Support, Non-U.S. Gov't