The aim of this survey is to ascertain if the incidence of isotretinoin exposed pregnancies was reduced by the late recommendations of prescription and issue (AMM modification on 06/08/2001 and 25/09/2001).
Service de Pharmacologie, Centre Régional de Pharmacovigilance et d'Information sur le médicament, Université François Rabelais, Hôpital Bretonneau, Tours.