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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1980-2-26
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pubmed:abstractText |
Urinary acid mucopolysaccharides (AMPS) excretion was investigated in a Japanese case with Multiple Sulfatase Deficiency (MSD) (Mucosulfatidosis). The patient excreted AMPS 4 to 5 times more (as carbazoluronic acid) than controls. The cellulose acetate gel electrophoresis clearly indicated two major AMPS which co-migrated with heparan sulfate and chondroitin sulfate A/C. Enzymic digestion with chondroitinase AC and ABC, and by testicular hyaluronidase plus amino sugar analysis also confirmed that our case excreted heparan sulfate and chondroitin sulfate A/C. These findings suggest that there are heterogeneities of urinary AMPS excretion among cases with MSD.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0340-6199
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
207-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:159821-Child,
pubmed-meshheading:159821-Chondroitin Sulfates,
pubmed-meshheading:159821-Glycosaminoglycans,
pubmed-meshheading:159821-Heparitin Sulfate,
pubmed-meshheading:159821-Humans,
pubmed-meshheading:159821-Leukodystrophy, Metachromatic,
pubmed-meshheading:159821-Male,
pubmed-meshheading:159821-Sulfatases
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pubmed:year |
1979
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pubmed:articleTitle |
Urinary acid mucopolysaccharides in multiple sulfatase deficiency (mucosulfatidosis).
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pubmed:publicationType |
Journal Article,
Case Reports
|