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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-7-12
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pubmed:abstractText |
Since human peripheral eosinophils have been shown to migrate to the CXC chemokine receptor 3 (CXCR3) ligands IFN-gamma-inducible protein 10 (IP10) and monokine induced by IFN-gamma (Mig), this confirms that CXCR3 is functionally expressed on these cells. IP10 expression has been shown to be increased in the airways of asthmatics. Eosinophil accumulations are found in bronchoalveolar lavage fluid (BALF) from patients with chronic eosinophilic pneumonia (CEP). To examine the contribution of IP10 and Mig in the pathogenesis of CEP, we measured the concentration of IP10 and Mig, and evaluated the expression of CXCR3 on eosinophils in BALF taken from patients with CEP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CXCL10 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CXCL9 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CXCR3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL10,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CXCL9,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/IP10-Mig receptor,
http://linkedlifedata.com/resource/pubmed/chemical/Intercellular Signaling Peptides...,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CXCR3,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytokine
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1018-2438
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2005 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-35
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:15956791-Adult,
pubmed-meshheading:15956791-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:15956791-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15956791-Chemokine CXCL10,
pubmed-meshheading:15956791-Chemokine CXCL9,
pubmed-meshheading:15956791-Chemokines, CXC,
pubmed-meshheading:15956791-Chronic Disease,
pubmed-meshheading:15956791-Eosinophils,
pubmed-meshheading:15956791-Female,
pubmed-meshheading:15956791-Humans,
pubmed-meshheading:15956791-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:15956791-Ligands,
pubmed-meshheading:15956791-Male,
pubmed-meshheading:15956791-Middle Aged,
pubmed-meshheading:15956791-Patients,
pubmed-meshheading:15956791-Pneumonia,
pubmed-meshheading:15956791-Pulmonary Eosinophilia,
pubmed-meshheading:15956791-Receptors, CXCR3,
pubmed-meshheading:15956791-Receptors, Chemokine,
pubmed-meshheading:15956791-Receptors, Cytokine
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pubmed:year |
2005
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pubmed:articleTitle |
Accumulation of CXCR3-expressing eosinophils and increased concentration of its ligands (IP10 and Mig) in bronchoalveolar lavage fluid of patients with chronic eosinophilic pneumonia.
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pubmed:affiliation |
Department of Cell Regulation, School of Medicine, Kagawa University, Kita-gun, Kagawa, Japan. kshigeki@med.kagawa-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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