|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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|
pubmed:dateCreated |
2005-6-15
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|
pubmed:abstractText |
There is an increasing body of evidence that magnetic resonance imaging-occult tissue damage is an important component of primary progressive multiple sclerosis (PPMS) pathology. Proton magnetic resonance spectroscopy (1H-MRS) can be used to measure in vivo whole-brain N-acetylaspartate (WBNAA) concentrations, the decrease of whose levels is considered a marker of neuronal-axonal injury.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0003-9942
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
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pubmed:volume |
62
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
898-902
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|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:15956160-Adult,
pubmed-meshheading:15956160-Aged,
pubmed-meshheading:15956160-Aspartic Acid,
pubmed-meshheading:15956160-Atrophy,
pubmed-meshheading:15956160-Axons,
pubmed-meshheading:15956160-Biological Markers,
pubmed-meshheading:15956160-Brain,
pubmed-meshheading:15956160-Female,
pubmed-meshheading:15956160-Humans,
pubmed-meshheading:15956160-Magnetic Resonance Spectroscopy,
pubmed-meshheading:15956160-Male,
pubmed-meshheading:15956160-Middle Aged,
pubmed-meshheading:15956160-Multiple Sclerosis, Chronic Progressive
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Axonal injury and overall tissue loss are not related in primary progressive multiple sclerosis.
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|
pubmed:affiliation |
Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
