Linked Life Data

15925779

Source:http://linkedlifedata.com/resource/pubmed/id/15925779

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-5-31
pubmed:abstractText
Topical hemostatic agents are widely and safely used in neurosurgery. The purpose of this study was to compare and analyse the early tissue reactions to two hemostatic agents, oxidized regenerated cellulose and gelatin sponge, in rabbit brain by magnetic resonance imaging and histopathologic sections. Bilateral identical parenchymal lesions were made in the frontal regions of each hemisphere in 13 rabbits. Hemostasis was achieved using oxidized regenerated cellulose or gelatin sponge, one agent being used on each side. Cranial magnetic resonance imaging was performed 24 h postoperatively and there was no statistical difference in edema formation at the site of the lesions. Histopathologic examinations indicated that pericapillary edema and endothelial distortion were common in both groups but that there was additional tissue degeneration evident in the regions where gelatin sponge had been used. Oxidized regenerated cellulose seemed to cause greater tissue distortion in magnetic resonance images than gelatin sponge but in contrast, histological examination of lesions in which oxidized regenerated cellulose had been used revealed less tissue degeneration than histopathologic examinations of lesions in which gelatin sponge had been used.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0967-5868
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
445-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Radiological and histopathological examination of early tissue reactions to absorbable hemostatic agents in the rabbit brain.
pubmed:affiliation
Department of Neurosurgery, Gazi University Medical School, Ankara, Turkey. akaymaz@gazi.edu.tr
pubmed:publicationType
Journal Article, Comparative Study