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| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0132800 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0596902 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C1611588 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0599682 | lld:lifeskim |
| pubmed-article:15916437 | lifeskim:mentions | umls-concept:C0205198 | lld:lifeskim |
| pubmed-article:15916437 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:15916437 | pubmed:dateCreated | 2005-5-26 | lld:pubmed |
| pubmed-article:15916437 | pubmed:abstractText | 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters (8a-h) showed high affinity for the norepinephrine transporter (NET). The most potent and selective compound was 3alpha-(3-fluoro-4-methylphenyl)nortropane-2beta-carboxylic acid methyl ester (8d), with a Ki of 0.43 nM at the NET and 21- and 55-fold selectivity relative to binding at the dopamine and serotonin transporters. The development of 8d makes available compounds selective for all three transporters from the same structural class. | lld:pubmed |
| pubmed-article:15916437 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15916437 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15916437 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15916437 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:15916437 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15916437 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:15916437 | pubmed:issn | 0022-2623 | lld:pubmed |
| pubmed-article:15916437 | pubmed:author | pubmed-author:KuharMichael... | lld:pubmed |
| pubmed-article:15916437 | pubmed:author | pubmed-author:CarrollF... | lld:pubmed |
| pubmed-article:15916437 | pubmed:author | pubmed-author:BloughBruce... | lld:pubmed |
| pubmed-article:15916437 | pubmed:author | pubmed-author:TyagiSameerS | lld:pubmed |
| pubmed-article:15916437 | pubmed:author | pubmed-author:NavarroHernn... | lld:pubmed |
| pubmed-article:15916437 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15916437 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:15916437 | pubmed:volume | 48 | lld:pubmed |
| pubmed-article:15916437 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15916437 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15916437 | pubmed:pagination | 3852-7 | lld:pubmed |
| pubmed-article:15916437 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:15916437 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15916437 | pubmed:articleTitle | Synthesis and monoamine transporter binding properties of 3alpha-(substituted phenyl)nortropane-2beta-carboxylic acid methyl esters. Norepinephrine transporter selective compounds. | lld:pubmed |
| pubmed-article:15916437 | pubmed:affiliation | Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, North Carolina 27709, USA. fic@rti.org | lld:pubmed |
| pubmed-article:15916437 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15916437 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:15916437 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:15916437 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:15916437 | lld:chembl |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15916437 | lld:pubmed |
