Source:http://linkedlifedata.com/resource/pubmed/id/15912392
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5-6
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pubmed:dateCreated |
2005-7-26
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pubmed:abstractText |
The P-glycoprotein, a product of MDR1 (multiple drug resistance 1) gene, is a membrane efflux pump localized in epithelial cells in the small and large intestine, a part of the gastrointestinal barrier that protects cells against xenobiotics from our diet, bacterial toxins, drugs and other biologically active compounds, possibly carcinogens. In the present study, an association of MDR1 gene polymorphism and the occurrence of colon cancer were evaluated.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0031-6970
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
389-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15912392-Adult,
pubmed-meshheading:15912392-Age of Onset,
pubmed-meshheading:15912392-Aged,
pubmed-meshheading:15912392-Aged, 80 and over,
pubmed-meshheading:15912392-Colonic Neoplasms,
pubmed-meshheading:15912392-Female,
pubmed-meshheading:15912392-Gene Frequency,
pubmed-meshheading:15912392-Genotype,
pubmed-meshheading:15912392-Humans,
pubmed-meshheading:15912392-Male,
pubmed-meshheading:15912392-Middle Aged,
pubmed-meshheading:15912392-P-Glycoprotein,
pubmed-meshheading:15912392-Poland,
pubmed-meshheading:15912392-Polymorphism, Genetic
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pubmed:year |
2005
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pubmed:articleTitle |
Polymorphism in the P-glycoprotein drug transporter MDR1 gene in colon cancer patients.
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pubmed:affiliation |
Department of Pharmacology, Pomeranian Medical University, Powsta?ców Wlkp. 72 Str, 70-111, Szczecin, Poland. mkurz@op.pl
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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