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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-4-8
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pubmed:abstractText |
The prognosis in patients with hyperdynamic septic shock correlates with the presence and the severity of septic encephalopathy. However, the neurological evaluation is considerably influenced by the use of analgesia sedation during mechanical ventilation. An early concentration peak of the neuroprotein S-100B in serum reflects both cellular damage at an increased permeability of the blood-brain-barrier and a delayed renal elimination. Thus, the objective of this study was to analyze the effect of continuous veno-venous hemofiltration (CVVH) on early S-100B serum levels in septic shock patients, who were treated with either stress doses of hydrocortisone or placebo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0949-2321
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
81-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15817428-Adult,
pubmed-meshheading:15817428-Aged,
pubmed-meshheading:15817428-Anti-Inflammatory Agents,
pubmed-meshheading:15817428-Dose-Response Relationship, Drug,
pubmed-meshheading:15817428-Double-Blind Method,
pubmed-meshheading:15817428-Female,
pubmed-meshheading:15817428-Hemofiltration,
pubmed-meshheading:15817428-Humans,
pubmed-meshheading:15817428-Hydrocortisone,
pubmed-meshheading:15817428-Male,
pubmed-meshheading:15817428-Middle Aged,
pubmed-meshheading:15817428-Nerve Growth Factors,
pubmed-meshheading:15817428-Placebos,
pubmed-meshheading:15817428-Prognosis,
pubmed-meshheading:15817428-Prospective Studies,
pubmed-meshheading:15817428-S100 Proteins,
pubmed-meshheading:15817428-Sensitivity and Specificity,
pubmed-meshheading:15817428-Shock, Septic
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pubmed:year |
2005
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pubmed:articleTitle |
Hemofiltration does not influence early S-100B serum levels in septic shock patients receiving stress doses of hydrocortisone or placebo.
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pubmed:affiliation |
Department of Surgery Innenstadt, Klinikum der Universität München, Germany. Thomas.Mussack@med.uni-muenchen.de
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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