Linked Life Data

15801577

Source:http://linkedlifedata.com/resource/pubmed/id/15801577

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-4-1
pubmed:abstractText
The present study was to evaluate the effects of chronic cigarette smoke exposure on lipid peroxidation in various organ tissues. Sprague-Dawley rats were exposed to passive smoking 2 hr per day, 6 days per week (Monday-Saturday), for 24 weeks. Malondialdehyde levels, as an index of lipid peroxidation, were measured by the thiobarbituric acid assay. Levels were significantly higher in tissues of passive-smoke-exposed groups (n=10) compared with normal-bred control groups (n=6), for red blood cells (2.17+/-0.22 vs. 1.80+/-0.39 nmol/mg), lung (1.39+/-0.32 vs. 1.03+/-0.35 nmol/mg), and spleen (1.75+/-0.33 vs. 1.42+/-0.15 nmol/mg); p<.05. No differences in malondialdehyde levels were found in plasma, heart, liver, stomach, and renal tissues. The results suggest that chronic environmental tobacco smoke exposure can increase lipid peroxidation in red blood cells and in lung and spleen tissue. This finding brings further investigative attention to the public health issue of the injurious effects of chronic passive smoke exposure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1462-2203
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1039-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Tissue levels of malondialdehyde after passive smoke exposure of rats for a 24-week period.
pubmed:affiliation
Smoking Cessation Clinic, Department of Family Medicine, Keimyung University Medical School, Daegu, Korea. dhkim@dsmc.or.kr
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Evaluation Studies