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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1992-6-10
|
| pubmed:abstractText |
Tumour necrosis factor alpha (TNF) is a cytokine produced by mononuclear phagocytes (MP) originally discovered for its cytotoxic activity on tumour cell targets. It was subsequently demonstrated that, in addition to its oncolytic potential, TNF exerts a wide variety of activities on the host defensive system against malignancies. This article briefly reviews the current concepts on the role of TNF in the antitumour activity of MP.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0025-7931
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
59 Suppl 1
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
47-9
|
| pubmed:dateRevised |
2009-11-11
|
| pubmed:meshHeading |
pubmed-meshheading:1579736-Cytotoxicity, Immunologic,
pubmed-meshheading:1579736-Humans,
pubmed-meshheading:1579736-Killer Cells, Natural,
pubmed-meshheading:1579736-Major Histocompatibility Complex,
pubmed-meshheading:1579736-Neoplasms,
pubmed-meshheading:1579736-Phagocytes,
pubmed-meshheading:1579736-Tumor Necrosis Factor-alpha
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Antitumour activity of mononuclear phagocytes: role of tumour necrosis factor alpha.
|
| pubmed:affiliation |
Consiglio Nazionale delle Ricerche, Istituto di Fisiopatologia Respiratoria, Università di Palermo, Italy.
|
| pubmed:publicationType |
Journal Article,
Review
|