Source:http://linkedlifedata.com/resource/pubmed/id/15776145
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-3-18
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pubmed:abstractText |
Hip is a site very commonly affected by osteoarthritis (OA), yet few data exist in literature regarding intra-articular use of hyaluronic acid in this pathology. We evaluated the efficacy of Hylan G-F 20 hip viscosupplementation performed under ultrasound guidance. We enrolled 26 patients affected by symptomatic hip OA and treated them with a single intraarticular injection of Hylan G-F 20, which could be repeated every two months. The injection was performed under ultrasound guidance with an antero-superior approach. Treatment efficacy was assessed through Lequesne index, visual analogue scale (VAS) pain quantification, and NSAID intake at the timepoint zero (baseline), and after 2, 6 and 12 months. We observed a statistically significant reduction of all considered parameters at the timepoints 2 and 6 months, when compared to baseline. At 12 months the changes were still statistically significant for all parameters for about 50% of the patients. No side effect was observed, nor systemic complication. Viscosupplementation is a promising approach for hip OA, although further and wider studies are wanted to determine how long the beneficial effect lasts, and what is the optimal number of injections to administer.
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pubmed:language |
ita
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0048-7449
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-43
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15776145-Aged,
pubmed-meshheading:15776145-Aged, 80 and over,
pubmed-meshheading:15776145-Female,
pubmed-meshheading:15776145-Follow-Up Studies,
pubmed-meshheading:15776145-Humans,
pubmed-meshheading:15776145-Hyaluronic Acid,
pubmed-meshheading:15776145-Injections, Intra-Articular,
pubmed-meshheading:15776145-Injections, Intralesional,
pubmed-meshheading:15776145-Male,
pubmed-meshheading:15776145-Middle Aged,
pubmed-meshheading:15776145-Osteoarthritis, Hip,
pubmed-meshheading:15776145-Pilot Projects,
pubmed-meshheading:15776145-Prospective Studies
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pubmed:articleTitle |
[Intra-articular treatment with Hylan G-F 20 under ultrasound guidance in hip osteoarthritis. Clinical results after 12 months follow-up].
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pubmed:affiliation |
Dipartimento di Medicina Interna, Ospedale S.Pietro-Fatebenefratelli, Via Cassia, 600-00192 Rome. alberto.migliore@tin.it
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
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