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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-3-14
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pubmed:abstractText |
Activation-induced cell death (AICD) is a major mechanism in the regulation of peripheral tolerance and its impairment can determine the development of autoimmunity. In the present study, in order to evaluate the role of caspase-3 in type 1 diabetes mellitus (T1DM) AICD, caspase-3 expression was analyzed in peripheral blood lymphocytes from 37 new onset T1DM patients and from 36 normal control subjects (NC) in resting conditions and after anti-Fas-triggered apoptosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0804-4643
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
152
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-25
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15762195-Adolescent,
pubmed-meshheading:15762195-Adult,
pubmed-meshheading:15762195-Antigens, CD95,
pubmed-meshheading:15762195-Apoptosis,
pubmed-meshheading:15762195-Caspase 3,
pubmed-meshheading:15762195-Caspases,
pubmed-meshheading:15762195-Child,
pubmed-meshheading:15762195-Diabetes Mellitus, Type 1,
pubmed-meshheading:15762195-Female,
pubmed-meshheading:15762195-Humans,
pubmed-meshheading:15762195-Immunoblotting,
pubmed-meshheading:15762195-Lymphocyte Activation,
pubmed-meshheading:15762195-Male,
pubmed-meshheading:15762195-RNA, Messenger,
pubmed-meshheading:15762195-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15762195-T-Lymphocytes
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pubmed:year |
2005
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pubmed:articleTitle |
Defective lymphocyte caspase-3 expression in type 1 diabetes mellitus.
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pubmed:affiliation |
Department of Clinical Sciences-Endocrinology, University La Sapienza, Rome, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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