Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1992-5-28
pubmed:abstractText
Recombinant Interleukin-1 alpha (IL-1 alpha), Interleukin-2 (IL-2) and recombinant macrophage colony-stimulating factor-1 (M-CSF-1) as well as combinations of IL-2 and M-CSF-1 were studied for their ability to protect seven-day-old C57BL/6 mice against HSV-1 infection. Treatment of the mice with IL-2, M-CSF-1 or combinations of IL-2 and M-CSF-1 significantly increased survival rates. Treatment with IL-1 alpha (10 U and 100 U/mouse) was most effective in protection against HSV-1, resulting in significantly increased survival rates more than four times greater than the survival rate of the infected control group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0304-8608
pubmed:author
pubmed:issnType
Print
pubmed:volume
124
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-93
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Recombinant interleukin-1 alpha, interleukin-2 and M-CSF-1 enhance the survival of newborn C57BL/6 mice inoculated intraperitoneally with a lethal dose of herpes simplex virus-1.
pubmed:affiliation
Department of Molecular Virology, Faculty of Medicine, Hebrew University of Jerusalem, Israel.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't