Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-1-17
pubmed:abstractText
Resin (co)monomers may be released from restorative dental materials and can diffuse into the tooth pulp or the gingiva, and can reach the saliva and the circulating blood. Genotoxic potential of some dental composite components has been clearly documented. The genotoxic effects of xenobiotics can represent a possible step in tumor initiation and/or embryotoxicity/teratogenesis. A modified fluorescent mouse embryonic stem cell test (R.E.Tox) was used to test the embryotoxic potential of following dental restorative materials: Bisphenol A glycidylmethacrylate (BisGMA), urethanedimethacrylate (UDMA), hydroxyethylmethacrylate (HEMA), and triethyleneglycoldimethacrylate (TEGDMA), as well as some of their metabolic intermediates 2,3-epoxy-2-methyl-propionicacid-methylester (EMPME), methacrylic acid (MA), and 2,3-epoxy-2-methylpropionic acid (EMPA).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Bisphenol A-Glycidyl Methacrylate, http://linkedlifedata.com/resource/pubmed/chemical/Composite Resins, http://linkedlifedata.com/resource/pubmed/chemical/Epoxy Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Methacrylates, http://linkedlifedata.com/resource/pubmed/chemical/Polyethylene Glycols, http://linkedlifedata.com/resource/pubmed/chemical/Polymethacrylic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Polyurethanes, http://linkedlifedata.com/resource/pubmed/chemical/Propionic Acids, http://linkedlifedata.com/resource/pubmed/chemical/hydroxyethyl methacrylate, http://linkedlifedata.com/resource/pubmed/chemical/methacrylic acid, http://linkedlifedata.com/resource/pubmed/chemical/triethylene glycol dimethacrylate, http://linkedlifedata.com/resource/pubmed/chemical/urethane dimethacrylate luting resin
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0300-5712
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-55
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15652168-Animals, pubmed-meshheading:15652168-Bisphenol A-Glycidyl Methacrylate, pubmed-meshheading:15652168-Cell Differentiation, pubmed-meshheading:15652168-Cell Survival, pubmed-meshheading:15652168-Cells, Cultured, pubmed-meshheading:15652168-Composite Resins, pubmed-meshheading:15652168-Dental Restoration, Permanent, pubmed-meshheading:15652168-Embryo, Mammalian, pubmed-meshheading:15652168-Epoxy Compounds, pubmed-meshheading:15652168-Heart, pubmed-meshheading:15652168-Materials Testing, pubmed-meshheading:15652168-Methacrylates, pubmed-meshheading:15652168-Mice, pubmed-meshheading:15652168-Polyethylene Glycols, pubmed-meshheading:15652168-Polymethacrylic Acids, pubmed-meshheading:15652168-Polyurethanes, pubmed-meshheading:15652168-Propionic Acids, pubmed-meshheading:15652168-Stem Cells, pubmed-meshheading:15652168-Toxicity Tests
pubmed:year
2005
pubmed:articleTitle
In vitro embryotoxicity assessment with dental restorative materials.
pubmed:affiliation
Axiogenesis AG, Joseph-Stelzmann-Str. 50, 50931 Köln, Germany.
pubmed:publicationType
Journal Article