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pubmed-article:15639484pubmed:abstractTextIn the early phase after transmural myocardial infarction (MI), the infarcted myocardium undergoes replacement by scar tissue, which is essential for preserving the structural integrity of the infarcted tissue. Transforming growth factor (TGF)-beta1, which is known as a fibrotic cytokine, plays a pivotal role in the reparative fibrosis after MI. It is reported that granulocyte colony-stimulating factor (G-CSF) can accelerate wound healing. The aim of our study was to investigate the effect of G-CSF on early ventricular expansion after MI.lld:pubmed
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pubmed-article:15639484pubmed:articleTitleGranulocyte colony-stimulating factor attenuates early ventricular expansion after experimental myocardial infarction.lld:pubmed
pubmed-article:15639484pubmed:affiliationDivision of Cardiology, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.lld:pubmed
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