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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-1-10
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pubmed:abstractText |
In the early phase after transmural myocardial infarction (MI), the infarcted myocardium undergoes replacement by scar tissue, which is essential for preserving the structural integrity of the infarcted tissue. Transforming growth factor (TGF)-beta1, which is known as a fibrotic cytokine, plays a pivotal role in the reparative fibrosis after MI. It is reported that granulocyte colony-stimulating factor (G-CSF) can accelerate wound healing. The aim of our study was to investigate the effect of G-CSF on early ventricular expansion after MI.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
446-56
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15639484-Animals,
pubmed-meshheading:15639484-Blotting, Western,
pubmed-meshheading:15639484-Collagen,
pubmed-meshheading:15639484-Fibrosis,
pubmed-meshheading:15639484-Granulocyte Colony-Stimulating Factor,
pubmed-meshheading:15639484-Immunohistochemistry,
pubmed-meshheading:15639484-Leukocyte Count,
pubmed-meshheading:15639484-Male,
pubmed-meshheading:15639484-Myocardial Infarction,
pubmed-meshheading:15639484-Myocardium,
pubmed-meshheading:15639484-Neutrophils,
pubmed-meshheading:15639484-RNA, Messenger,
pubmed-meshheading:15639484-Rats,
pubmed-meshheading:15639484-Rats, Wistar,
pubmed-meshheading:15639484-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15639484-Transforming Growth Factor beta,
pubmed-meshheading:15639484-Transforming Growth Factor beta1,
pubmed-meshheading:15639484-Ventricular Remodeling
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pubmed:year |
2005
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pubmed:articleTitle |
Granulocyte colony-stimulating factor attenuates early ventricular expansion after experimental myocardial infarction.
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pubmed:affiliation |
Division of Cardiology, Department of Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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