Linked Life Data

15638407

Source:http://linkedlifedata.com/resource/pubmed/id/15638407

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2005-1-10
pubmed:abstractText
Uraemic patients frequently demonstrate tendencies towards life-threatening bleeding. Reduced platelet counts and their functional immaturity seem to be caused, among other things, by disorders in the system of marrow megakaryocytes. The aim of the study was a histomorphometric evaluation of marrow megakaryocytes in the course of experimental uraemia in rats. Uraemia was induced by means of right nephrectomy and a partial removal of the left kidney cortex in rats. Morphometric analysis was conducted, using the Microlmage program set. The number of MK, MK area, N/C, CDMK, CDNMK and MK cluster formation were analysed. Uraemic rats showed a reduction in the MK count and their area and an increase in the N/C ratio, CDMK, CDNMK and in the incidence of MK clusters. The results indicate that platelet disorders, observed in uraemia, can also be conditioned by disturbed maturation of MK.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:author
pubmed:volume
49 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-60
pubmed:dateRevised
2006-1-6
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Histomorphometry of marrow megakaryocytes in experimental uraemia in rats.
pubmed:affiliation
Department of Human Anatomy, Medical University of Bialystok, Poland. anatomia@amb.edu.pl
pubmed:publicationType
Journal Article