| pubmed-article:15589049 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:15589049 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
| pubmed-article:15589049 | lifeskim:mentions | umls-concept:C1622501 | lld:lifeskim |
| pubmed-article:15589049 | lifeskim:mentions | umls-concept:C0164209 | lld:lifeskim |
| pubmed-article:15589049 | lifeskim:mentions | umls-concept:C1254042 | lld:lifeskim |
| pubmed-article:15589049 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:15589049 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:15589049 | pubmed:dateCreated | 2004-12-13 | lld:pubmed |
| pubmed-article:15589049 | pubmed:abstractText | Circulating monocytic cells may mediate neuroinvasion in transmissible spongiform encephalopathies by transporting prion protein (PrP) from sites of entry to the nervous system. Factors regulating monocyte-derived dendritic cell (DC) functions in neuronal tissue include neurogenic mediators, but their interactions with prion-infected DCs are unknown. Here, we report that neuropeptides regulate the interaction of DCs exposed to PrP(106-126). Inhibition of neurokinin-1-receptors activation with neurokinin-1-receptor antagonist or antibody attenuates substance P-induced enhancement of DC migration induced by PrP(106-126) and prion-protein-induced DC maturation. Other neuropeptides arrest chemotaxis. Data support a priming role of the neuropeptide substance P in PrP(106-126)-induced migration of DCs involving neurokinin-1-receptors. | lld:pubmed |
| pubmed-article:15589049 | pubmed:language | eng | lld:pubmed |
| pubmed-article:15589049 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:15589049 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:15589049 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:15589049 | pubmed:issn | 0165-5728 | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:KaneiderNicol... | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:DunzendorferS... | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:WiedermannChr... | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:PatschJosef... | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:KaserArthurA | lld:pubmed |
| pubmed-article:15589049 | pubmed:author | pubmed-author:TilgHerbertH | lld:pubmed |
| pubmed-article:15589049 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:15589049 | pubmed:volume | 158 | lld:pubmed |
| pubmed-article:15589049 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:15589049 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:15589049 | pubmed:pagination | 153-8 | lld:pubmed |
| pubmed-article:15589049 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:meshHeading | pubmed-meshheading:15589049... | lld:pubmed |
| pubmed-article:15589049 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:15589049 | pubmed:articleTitle | Neurokinin-1 receptor interacts with PrP(106-126)-induced dendritic cell migration and maturation. | lld:pubmed |
| pubmed-article:15589049 | pubmed:affiliation | Division of General Internal Medicine, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria. | lld:pubmed |
| pubmed-article:15589049 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:15589049 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15589049 | lld:pubmed |
